SportLogia
Vol. 9, Issue 1, June 2013.

 

FREQUENCY OF ANAEROBIC POWER AMONG BRAZILIANS BASED ON DERMATOGLYPHICS AND R577X POLYMORPHISM OF THE ACTN3 PROTEIN

 

Carlos Renato Paz1,3,6, Ramon Cunha Montenegro1,2,3, Eric de Lucena Barbosa1,2,6,
Asdrúbal Nóbrega Montenegro-Neto2, Sérgio Marques de Lucena4,
Vanduir Soares de Araújo Filho2,4,6, Paula Roquetti Fernandes5,6, and José Fernandes Filho1,5,6
1Autonomous University of Asunción – UAA/Asunción-PY; Paraguay
2Physical Evaluation Laboratory – UNIPÊ – SANNY, João Pessoa, Paraíba, Brazil
3Federal Institute of Education, Science and Technology of Paraíba – IFPB, João Pessoa,
Paraíba, Brazil
4Scientific Policing Institute of Paraíba SPI-PB, João Pessoa, Paraíba, Brazil
5Center of Excellence in Physical Evaluation – CEAF, Rio de Janeiro, Brazil
6 LABIMH-UFRJ - Research Group, Rio de Janeiro, Brazil

 

 

OWERVIEW PAPER
doi: 10.5550/sgia.130901.en.006P
UDC: 796.012.1:159.928.23-05(=436)

  

 

Summary  

FULL TEXT (.pdf)

Dermatoglyphics and analysis of the Alpha-Actinin-3 gene are evaluative instruments frequently used to identify the sportive and general population profile associated with physical performance. This research aimed to determine, based on dermatoglyphic characteristics and the R577X polymorphism of Alpha-Actinin-3, the percentage of people in the State of Paraíba/Brazil, with unfavorable characteristics to excelling in sports that require anaerobic power. A descriptive study of profiles, with ex post facto typology, was performed. The dermatoglyphic fingerprint characteristics of 309 people (149 males and 160 females) were identified, and ACTN3 genotype was analyzed in 96 people (40 males and 56 females). The dermatoglyphic data indicated that 5.8% of the study population fit the classification of anaerobic muscle power predisposition, while 94.2% did not fit on it. The genetic frequency analysis indicated that 19.8% of subjects in the sample had the XX mutant genotype. These results represent a substantial error reduction in the search for and selection of athletes with the potential for high performance, especially in those sports that require AMP.

 

Key words: Alpha-actinin, Fingerprint, Genetic Polymorphism, Skeletal Muscle, Genotype frequency.

 

References

Abramova, T. F., Nikitina, T. M., & Ozolin, N. N. (1996). Dermatoglyphic prints. genetic markers in the potential energy of man. Moscow Scientific Annals, 3(13).

Berman, Y., & North, K. N. (2010). A gene for speed: The emerging role of α-actinin-3 in muscle metabolism. Physiology, 25, 250–259. doi: 10.1152/physiol.00008.2010; PMid: 20699471

Bogle, A. C., Reed, T., & Norton, J. A. (1994). Within-pair differences in a-b ridge count asymmetry in monozygotic twins: evidence for a placental proximity effect. Hum Hered, 44, 162–168. doi: 10.1159/000154209; PMid: 8039800

Bustamante-Ara, N., Santiago, C., Verde, Z., Yvert, T., Gómez-Gallego, F., Rodríguez-Romo, G., ... Lucia A. (2010). ACE and ACTN3 genes and muscle phenotypes in nonagenarians. Int J Sports Med, 31, 221–224.
doi: 10.1055/s-0030-1247529; PMid: 20148371

Cummins, H., & Midlo, C. H. (1961). Fingerprints, palms and soles: an introduction to dermatoglyphics. New York: Dover Publications Inc.

Druzhevskaya, A. M., Ahmetov, I. I., Astratenkova, I. V., & Rogozkin, V. A. (2008). Association of the ACTN3 R577X polymorphism with power athlete status in Russians. Eur J Appl Physiol, 103, 631–634. doi: 10.1007/s00421-008-0763-1; PMid: 18470530

Eynon, N., Duarte, J. A., Oliveira, J., Sagiv, M., Yamin, C., Meckel, ... Goldhammer, E. (2009). ACTN3 R577X Polymorphism and Israeli Top-level Athletes. Int J Sports Med, 30, 695–698. doi: 10.1055/s-0029-1220731; PMid: 19544227

Holdys, J., Kryściak, J., Stanisławski, D., & Gronek, P. (2011). Polymorphism of the α-actn3 gene in individuals practising different sports disciplines. Biol Sport, 28, 101–106. doi: 10.5604/942738

Junior, A. T. C., Cunha, A. C. P. T., Scheneider, A. T., & Dantas, P. M. S. (2006). Características dermatoglíficas, somatotípicas, psicológicas e fisiológicas da seleção brasileira feminina adulta de handebol [Features dermatoglyphics, somatotype, psychological and physiological of the Brazilian adult female handball]. Fit Perf J., 5, 81–86. doi: 10.3900/fpj.5.2.81.p

Kansal, D. K. (2010). A critical study of sports talent selection and promotion of sports participation, at young age. Br J Sports Med, 44, i65–i66. doi: 10.1136/bjsm.2010.078725.219

Klein, C. M. O., & Fernandes-Filho, J. (2003). Relação entre a dermatoglifia, as qualidades físicas e o nível maturacional de escolares adolescentes de ambos os sexos. Fit Perf J, 2, 321–329.

Kücken, M., & Newell A. C. (2005). Fingerprint formation. J Theor Biol, 235, 71–83.
doi: 10.1016/j.jtbi.2004.12.020; PMid: 15833314

Linhares, R. V., Matta, M. O., Lima, J. R. P., Dantas, P. M. S., Costa, M. B., Fernandes Filho, J. (2009). Efeitos da maturação sexual na composição corporal, nos dermatóglifos, no somatótipo e nas qualidades físicas básicas de adolescentes [Efeitos da maturação sexual na composição corporal, nos dermatóglifos, no somatótipo e nas qualidades físicas básicas de adolescentes]. Arq Bras Endocrinol Metab, 53, 47–54.
doi: 10.1590/S0004-27302009000100008
; PMid: 19347185

Macêdo, M. M., & Fernandes-Filho, J. (2003). Estudo das características dermatoglíficas, somatotípicas e das qualidades físicas básicas nos diversos estágios de maturação sexual [Study of dermatoglyphic characteristics, somatotype and basic physical qualities in different stages of sexual maturation]. Fit Perf J, 2, 315–320.
doi: 10.3900/fpj.2.6.315.s;
doi: 10.3900/fpj.2.6.315.p

McCauley, T., Mastana, S. S., & Folland, J. P. (2010). ACE I/D and ACTN3 R/X polymorphisms and muscle function and muscularity of older Caucasian men. Eur J Appl Physiol, 109, 269–277. doi: 10.1007/s00421-009-1340-y; PMid: 20069311

Mills, M. A., Yang, N., Weinberger, R. P., Vander Woude, D. L., Beggs, A. H., ... North, K. N. (2001). Differential expression of the actin-binding proteins, α-actinin-2 and -3, in different species: implications for the evolution of functional redundancy. Hum Mol Genet, 10, 1335–1346. doi: 10.1093/hmg/10.13.1335; PMid: 11440986

Moran, C. N., Yang, N., Bailey, M. E. S., Tsiokanos, A., Jamurtas, A., MacArthur, D. G., ... Wilson, R. H. (2007). Association analysis of the ACTN3 R577X polymorphism and complex quantitative body composition and performance phenotypes in adolescent Greeks. Eur J Hum Genet, 15, 88–93. doi: 10.1038/sj.ejhg.5201724; PMid: 17033684

Niemi, A. K., & Majamaa, K. (2005). Mitochondrial DNA and ACTN3 genotypes in Finnish elite endurance and sprint athletes. Eur J Hum Genet, 13, 965–969. doi: 10.1038/sj.ejhg.5201438; PMid: 15886711

Norman, B., Esbjörnsson, M., Rundqvist, H., Österlund, T., von Walden, F., & Tesch, P. A. (2009). Strength, power, fiber types, and mRNA expression in trained men and women with different ACTN3 R577X genotypes. J Appl Physiol, 106, 959–965. doi: 10.1152/japplphysiol.91435.2008; PMid: 19150855

North, K. N., Yang, N., Wattanasirichaigoon, D., Mills, M., Easteal, S., & Beggs, A. H. (1999). A common nonsense mutation results in alpha-actinin-3 deficiency in the general population. Nat Genet, 21, 353–354.
doi: 10.1038/7675; PMid: 10192379

Papadimitriou, I. D., Papadopoulos, C., Kouvatsi, A., & Triantaphyllidis, C. (2008). The ACTN3 gene in elite Greek track and field athletes. Int J Sports Med, 29, 352–355. doi: 10.1055/s-2007-965339; PMid: 17879893

Roth, S. M., Walsh, S., Liu, D., Metter, E. J., Ferrucci, L., & Hurley, B. F. (2008). The ACTN3 R577X nonsense allele is underrepresented in elite-level strength athletes. Eur J Hum Genet, 16, 391–394.
doi: 10.1038/sj.ejhg.5201964; PMid: 18043716; PMCid: 2668151

Ruiz, J. R., Arteta, D., Buxens, A., Artieda, M., Gómez-Gallego, F., Santiago, C., ... Lucia, A. (2010). Can we identify a power-oriented polygenic profile? J Appl Physiol, 108, 561–566. doi: 10.1152/japplphysiol.01242.2009; PMid: 20044471

Ruiz, J. R., del Valle, M. F., Verde, Z., Díez-Veja, I., Santiago, C., Yvert, T., ... Lucia, A. (2011). ACTN3 R577X polymorphism does not influence explosive leg muscle power in elite volleyball players. Scand J Med Sci Sports, 21, e34–41. doi: 10.1111/j.1600-0838.2010.01134.x; PMid:0561285

Scott, R. A., Irving, R., Irwin, l., Morrison, E., Charlton, V., Austin, K., ... Pitsiladis, Y. P. (2009). ACTN3 and ACE genotypes in elite Jamaican and US sprinters. Med Sci Sports Exerc, 42, 107–112.
doi: 10.1249/MSS.0b013e3181ae2bc0; PMid: 20010124

Walsh, P. S., Metzger, D. A., & Higuchi, R. (1991). Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. Biotechniques, 10, 506–513. PMid: 1867860

Yang, N., MacArthur, D. G., Gulbin, J. P., Hahn, A. G., Beggs, A. H., Easteal, S., & North, K. (2003). ACTN3 genotype is associated with human elite athletic performance. Am J Hum Genet, 73, 627–631. doi: 10.1086/377590; PMid: 12879365; PMCid: 1180686

Zary, J. C. F., & Fernandes-Filho, J. (2007). Identificação do Perfil Dermatoglífico e Somatotípico dos Atletas de voleibol masculino adulto, juvenil e infanto-juvenil, de alto rendimento no Brasil [Identification and Profile Dermatoglyphic somatotypical Athletes volleyball adult male, juvenile and juvenile, high yield in Brazil]. R bras Ci e Mov, 15, 53–60.

Zary, J. C., Reis, V. M., Rouboa, A., Silva, A. J., Fernandes, P. R., & Fernandes Filho, J. (2010). The somatotype and dermatoglyphic profiles of adult, junior and juvenile male Brazilian top-level volleyball players. Sci Sports, 25, 146–152. doi: 10.1016/j.scispo.2009.09.002

Zempo, H., Tanabe, K., Murakami, H., Iemitsu, M., Maeda, S., & Kuno, S. (2010). ACTN3 Polymorphism Affects Thigh Muscle Area. Int J Sports Med, 31, 138–142. doi: 10.1055/s-0029-1242808; PMid: 20222007